Designed to boost energy, focus, pump, and endurance + Burn Fat. Powered by natural caffeine sources, clinically dosed citrulline and Nitrosigine for nitric oxide, plus HMB for muscle support and Capsimax with CaloriBurn for thermogenesis.
No proprietary blends. Full transparency. Built to help you train harder, stay locked in, and push lean results.
Designed to boost energy, focus, pump, and endurance + Burn Fat. Powered by natural caffeine sources, clinically dosed citrulline and Nitrosigine for nitric oxide, plus HMB for muscle support and Capsimax with CaloriBurn for thermogenesis.
No proprietary blends. Full transparency. Built to help you train harder, stay locked in, and push lean results.
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Lab Tested
No Artificial Color
Quality Purity Guaranteed
Open, Non-Proprietary Formula
Properly Dosed, Premium Ingredients
100% Money Back Guarantee
Benefits
Each serving delivers full clinical doses to support energy, focus, endurance, and muscle pump, without relying on excessive stimulants. The caffeine is calibrated to provide clean, sustained energy so you can train hard without the crash or jitters.
To support body composition, this formula includes HMB, a well-researched ingredient shown to help preserve lean muscle during intense training and calorie-controlled phases. Maintaining lean muscle is critical for strength, performance, and a defined look.
For thermogenic support, CaloriBurn® and Capsimax® are included to support fat metabolism and energy expenditure. These ingredients work by supporting your body’s natural thermogenic processes, helping you train with intensity while pursuing a leaner physique.
Directions
Mix 8 oz of water per serving (30 min. before exercise). Begin with half a serving to assess tolerance. Continue with a full scoop once tolerance is acceptable. Do not take within 3 hours of sleep and other stimulants (Ex. Caffeine).
“Our products are only intended to be used by healthy individuals 18 years of age or older. By purchasing products from us, you confirm that you are at least 18 years old and do not have any pre-existing medical conditions.”
Lab Testing
1 UP Nutrition products are manufactured under strict quality standards in an NSF/ANSI cGMP 455-2 Certified and FDA-Registered Facility in Miami FL, USA. Every batch undergoes rigorous lab testing for formula accuracy, potency, purity, and safety to ensure we deliver the highest standards of quality.
*NSF-Certified facilities are recognized globally for their stringent quality control processes
Pure L Citrulline - Helps boosts nitric-oxide levels, which can help widen your blood vessels, allowing more oxygen and nutrients to be delivered to your muscles. It also has a role in the removal of ammonia, a compound known to cause exercise-related fatigue, from your blood
Nitrosigine® - The unique complex of arginine and silicon in Nitrosigine unlocks powerful synergistic effects that offer enhanced benefits. Arginine contributes to boosting nitric oxide (NO) levels, which has been shown to be a key factor in generating greater blood flow and vasodilation in working muscles. Meanwhile, silicon contributes to blood flow by strengthening and improving the flexibility of arterial walls. Together, these ingredients offer powerful efficacious results compared to each ingredient alone. Nitrosigine increases blood levels of arginine for up to six hours and elevates blood levels of silicon with a single dose.
InnovaBeanTM - Natural Caffeine from Green Coffee Bean - It provides clean smooth energy without jitters and crash. We prefer natural caffeine as a healthier option when compared to synthesized caffeine. We use trademarked - InnovaBeanTM
CognatiQ® - More focus with trademarked ingredient “CognatiQ® - an all-natural, patented extract of whole fruit from the Coffee arabica plant. Increases levels of a key neuroprotein (BDNF) vital to higher focus.
Capsimax® - Is a microencapsulated capsicum (capsaicinoid) extract designed to support thermogenesis, fat metabolism, and energy expenditure. Its controlled-release technology helps reduce gastric irritation and heat sensation, making it suitable for daily use in weight management and sports nutrition supplements.
Supplement Facts
Sour Watermelon
Sour Strawberry
Full Transparency
Our open, non-proprietary formula means you know exactly what you're paying for. Highest quality ingredients Dosed High, Dosed Right!
Not for use by individuals under the age of 18. Do not use if pregnant or nursing. Consult a physician before using this product if you are unaware of your health status or have a history of high blood pressure, heart disease or if you are using a monoamine oxidase inhibitor (MAOI) or any other dietary supplement. Do not use if you’re currently using a prescription drug, rover-the-counter drug containing but not limited to ibuprofen, ephedrine, pseudoephedrine, or phenylpropanolamine (ingredients found in certain allergy, asthma, cough or cold, and weight control products). Discontinue use if adverse reactions occur and consult a physician. Individuals who are sensitive to the effects of caffeine or have a medical condition should consult a licensed health care professional before consuming this product. If adverse reactions occur, then consult a physician. This product may contain ingredients banned by certain organizations. User assumes all risk, liabilities or consequences regarding testing.
Keep out reach of children.
Store at room temperature.
Store away from heat and moisture.
Tamper evident: do not use if seal under cap is broken or missing.
† These statements have not been evaluated by the Food and Drug Administration.
This product is not intended to diagnose, treat, cure or prevent any disease.
Allergen Warning:
Manufactured on equipment which processes products containing Milk, Eggs, Soy Beans, Fish Oil, Tree Nuts, and Peanuts.
Reviews
Supplement Facts
Sour Watermelon
Sour Strawberry
Full Transparency
Our open, non-proprietary formula means you know exactly what you're paying for. Highest quality ingredients Dosed High, Dosed Right!
Each serving delivers full clinical doses to support energy, focus, endurance, and muscle pump, without relying on excessive stimulants. The caffeine is calibrated to provide clean, sustained energy so you can train hard without the crash or jitters.
To support body composition, this formula includes HMB, a well-researched ingredient shown to help preserve lean muscle during intense training and calorie-controlled phases. Maintaining lean muscle is critical for strength, performance, and a defined look.
For thermogenic support, CaloriBurn® and Capsimax® are included to support fat metabolism and energy expenditure. These ingredients work by supporting your body’s natural thermogenic processes, helping you train with intensity while pursuing a leaner physique.
Directions
Mix 8 oz of water per serving (30 min. before exercise). Begin with half a serving to assess tolerance. Continue with a full scoop once tolerance is acceptable. Do not take within 3 hours of sleep and other stimulants (Ex. Caffeine).
“Our products are only intended to be used by healthy individuals 18 years of age or older. By purchasing products from us, you confirm that you are at least 18 years old and do not have any pre-existing medical conditions.”
Lab Testing
1 UP Nutrition products are manufactured under strict quality standards in an NSF/ANSI cGMP 455-2 Certified and FDA-Registered Facility in Miami FL, USA. Every batch undergoes rigorous lab testing for formula accuracy, potency, purity, and safety to ensure we deliver the highest standards of quality.
*NSF-Certified facilities are recognized globally for their stringent quality control processes
Pure L Citrulline - Helps boosts nitric-oxide levels, which can help widen your blood vessels, allowing more oxygen and nutrients to be delivered to your muscles. It also has a role in the removal of ammonia, a compound known to cause exercise-related fatigue, from your blood
Nitrosigine® - The unique complex of arginine and silicon in Nitrosigine unlocks powerful synergistic effects that offer enhanced benefits. Arginine contributes to boosting nitric oxide (NO) levels, which has been shown to be a key factor in generating greater blood flow and vasodilation in working muscles. Meanwhile, silicon contributes to blood flow by strengthening and improving the flexibility of arterial walls. Together, these ingredients offer powerful efficacious results compared to each ingredient alone. Nitrosigine increases blood levels of arginine for up to six hours and elevates blood levels of silicon with a single dose.
InnovaBeanTM - Natural Caffeine from Green Coffee Bean - It provides clean smooth energy without jitters and crash. We prefer natural caffeine as a healthier option when compared to synthesized caffeine. We use trademarked - InnovaBeanTM
CognatiQ® - More focus with trademarked ingredient “CognatiQ® - an all-natural, patented extract of whole fruit from the Coffee arabica plant. Increases levels of a key neuroprotein (BDNF) vital to higher focus.
Capsimax® - Is a microencapsulated capsicum (capsaicinoid) extract designed to support thermogenesis, fat metabolism, and energy expenditure. Its controlled-release technology helps reduce gastric irritation and heat sensation, making it suitable for daily use in weight management and sports nutrition supplements.
Full Transparency
Our open, non-proprietary formula means you know exactly what you're paying for. Highest quality ingredients Dosed High, Dosed Right!
Not for use by individuals under the age of 18. Do not use if pregnant or nursing. Consult a physician before using this product if you are unaware of your health status or have a history of high blood pressure, heart disease or if you are using a monoamine oxidase inhibitor (MAOI) or any other dietary supplement. Do not use if you’re currently using a prescription drug, rover-the-counter drug containing but not limited to ibuprofen, ephedrine, pseudoephedrine, or phenylpropanolamine (ingredients found in certain allergy, asthma, cough or cold, and weight control products). Discontinue use if adverse reactions occur and consult a physician. Individuals who are sensitive to the effects of caffeine or have a medical condition should consult a licensed health care professional before consuming this product. If adverse reactions occur, then consult a physician. This product may contain ingredients banned by certain organizations. User assumes all risk, liabilities or consequences regarding testing.
Keep out reach of children.
Store at room temperature.
Store away from heat and moisture.
Tamper evident: do not use if seal under cap is broken or missing.
† These statements have not been evaluated by the Food and Drug Administration.
This product is not intended to diagnose, treat, cure or prevent any disease.
Allergen Warning:
Manufactured on equipment which processes products containing Milk, Eggs, Soy Beans, Fish Oil, Tree Nuts, and Peanuts.
Lab Tested
No Artificial Color
Quality Purity Guaranteed
Open, Non-Proprietary Formula
Properly Dosed, Premium Ingredients
100% Money Back Guarantee
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Overall rating: 4.7032967 / 5 from 91 reviews.
AI Generated Review Summary
Pre-Workout Tone & Define offers a well-rounded experience, providing energy, focus, and a pump. Customers appreciate its endurance-boosting properties and the absence of jitters. The taste is also praised for being satisfying and not too sweet.
"This natural pre has a great flavor, provides enough energy for weights and HIIT, plus gives good pumps." — Sherry C.
"I love this pre workout!" — Cortney H.
Reviews
Best Pre-Workout
"This is one of the best pre-workouts that I have tried in awhile. I love how only one scoop makes me feel and gives me a ton of energy, not only for my workout but throughout the day. I highly recommend this to anyone looking for something to give you an extra pump!"
— Chelsi G. (5/5)
This one is good! It
"This one is good! It has a little spice to it, but it still tastes great. It’s not harsh on my Stomach though I do only Take half a scoop."
— Casandra B. (5/5)
Burned my throat and gums
"This pre-workout burned my throat and my gums, most likely from the capsimax or the caloriburn ingredients. Unfortunately, they wouldn’t allow a return since it was more than 30 days after my purchase."
— Karol K. (1/5)
Pre-workout Sour Watermelon
"I love this stuff. I’ve been using it for a couple months now."
— Nancy T. (5/5)
Love the Pre Workout
"I’ve been loving the pre workout! I can definitely tell a difference in my ability to keep going when normally I would tire out and be ready to quit! Once again, 1 Up has hit the nail on the head with their products!"
— Deborah T. (5/5)
The taste is terrible! They
"The taste is terrible! They need to call it jalapeño grape not sour grape. It burns my throat when I drink it. The pre workout without the fat burn in it is good but I don’t recommend the fat burn one."
— Nick C. (1/5)
Great product.
"Gives me a good push to get through my workouts. Little tingling feel but I like that anyways. The energy level while working out is great."
— Robert M. (5/5)
There is some sort of
"There is some sort of spice to this so I have been mixing it with something else because it's a little harsh in the morning. But otherwise loving this new tone and define combo!"
— Candra K. (4/5)
Love it!!
"Great taste. Great Feeling. First thing I drink in the morning and MAN does it get me fired up to go to the gym."
— Jonathan S. (5/5)
I feel the pump but
"I feel the pump but I for sure do feel burning sensation on my throat lol"